| Antigen | A 16-aa peptide (#OX1R11-P) from rat OX1R/ Hcrtr1 (gene accession # P56718) and 16-aa peptide from human OX1R (gene accession # O43613) Designation (# OX1R12-P, control or blocking peptide) conjugated to KLH. Cat# OX1R11-P supplied as a mixture of both peptides; epitope location ~ ~N-terminus, Extracellular (OX1R11-P) and ~CT, Cytoplasmic domain (OX1R12-P) |
| Form | Antigen/blocking Peptide |
| Product Type | Peptide |
| SpCrossreactivity | Rat OX1R11-P is the same in mouse and 82% homologous with human OX1R. Human OX2R12-P is 100% conserved in chimp, pig, bovine, and 87% in rat and mouse. Since antibodies are made to a mixture of rat and human peptides that are conserved in several species, the antibodies (#OX1R11-S or OX1R11-A) are expected to have wide species reactivity. No significant homology is seen with OX2R or other G-protein-coupled receptors. Antibody crossreactivity in various species has not been confirmed |
| SpeciesReactivity | Rat |
| SugApplications | Control or blocking peptides are recommended for ELISA plate coating for direct ELISA testing of antibodies or competitive ELISA, and antibody blocking or neutralization. |