Catalog# Size Unit Price Quantity
BMP65-R-20 20 ug $700.00

Purified Recombinant Human BMP6 protein, Biologically active

AntigenThe human BMP-2 signal peptide and propeptides (aa residues 1-282 of human BMP-2) fused to the human BMP-6 mature chain (aa residues 382-513 of human BMP-6) was expressed in a mouse myeloma cell line, NSO. The mature recombinant human BMP-6, generated by the proteolytic removal of the signal peptide and propeptide, is a disulfide-linked homodimeric protein consisting of two 132aa residue subunits with a mol. mass of ~15kD. Due to glycosylation the rhBMP-5 migrates as an ~36kD protein under non-reducing conditions and as doublet of 18kD and 23kD protein under reducing conditions in SDS-PAGE. Purified recombinant human (cat # BMP65-R-10, and # BMP65-R-20) BMP-6 has endotoxin level (<1 ng/1 ug). The biological activity of rhBMP-6 was determined by its ability to induce alkaline Phosphatase production by ATDC5 chondrogenic cells (ED50 = 05-0.15ng/ml).
FormAntigen Proteins
Product TypeRecombinant Protein
SpeciesReactivityHuman

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